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Linezolid is an antibiotic used for the treatment of infections caused by Gram-positive bacteria that are resistant to other antibiotics. [9] [10] Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA).
If these drugs are misused or mismanaged, multidrug-resistant TB (MDR-TB) can develop. MDR-TB takes longer to treat with second-line drugs (i.e., amikacin, kanamycin, or capreomycin), which are more expensive and have more side-effects. XDR-TB can develop when these second-line drugs are also misused or mismanaged and become ineffective.
The Group A drugs are currently levofloxacin or moxifloxacin, bedaquiline and linezolid, therefore XDR-TB is MDR/RR-TB that is resistant to a fluoroquinolone and at least one of bedaquiline or linezolid (or both). In a study of MDR-TB patients from 2005 to 2008 in various countries, 43.7% had resistance to at least one second-line drug. [28]
It is a story that in its depiction of strategies, tactics and mindset should make us wonder about the prescription drugs that are so much a part of our lives. The show that Johnson & Johnson put on that morning for the analysts at the hotel, which the company owns, would produce positive headlines in the news that afternoon.
Not surprisingly, lower-income Americans are more likely to carry medical debt. So are rural Americans, and people living in the South. More surprising, perhaps, is the medical debt burden on seniors.
Why Snowflake isn't so expensive. Investors should question the narrative that Snowflake is expensive due to its price-to-sales ratio (P/S) of 16. SNOW PS Ratio Chart. SNOW P/S Ratio data by YCharts.
According to standard valuation metrics, such as the forward 12-month price-to-earnings or price-to-sales ratio, SoFi stock might easily appear expensive at 63 times earnings and 5.6 times forward ...
These drugs are listed here either because they are not very effective (e.g., clarithromycin) or because their efficacy has not been proven (e.g., linezolid, R207910). Rifabutin is effective, but is not included on the WHO list because, for most developing countries, it is impractically expensive. [medical citation needed]
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