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Leflunomide, sold under the brand name Arava among others, is an immunosuppressive disease-modifying antirheumatic drug , [8] used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase. [9] Bottle of Leflunomide (Arava) and tablet
The condition is commonly associated with vascular and cardiac changes associated with aging but can be caused by many other conditions, including congestive heart failure, kidney failure, liver cirrhosis, portal hypertension, trauma, alcoholism, altitude sickness, pregnancy, hypertension, sickle cell anemia, a compromised lymphatic system or merely long periods of time sitting or standing ...
Ankle-brachial index (ABI) testing to compare blood pressure in your ankle and arm to help detect peripheral artery disease. Electrocardiogram (ECG) to measure the electrical activity of your heart
In cases of swelling, the extremities' circumference is measured over time for reference. In early stages of lymphedema, elevating the limb may reduce or eliminate the swelling. Palpation of the wrist or ankle can determine the degree of swelling; assessment includes a check of the pulses.
An imbalance can cause fluid overload in the spaces between cells or tissues, which can lead to edema, per the National Institutes of Health. Edema refers to the swelling that happens when the ...
The most common side effects of bicalutamide monotherapy in men include breast tenderness, breast growth, feminization, demasculinization, and hot flashes. Less common side effects of bicalutamide monotherapy in men include sexual dysfunction, depression, fatigue, weakness, and anemia. Bicalutamide is well tolerated and has few side effects in ...
This inflammation can cause pain and stiffness [5] and is one of the most common causes of ankle problems. [ 7 ] In many types of arthritis, progressive joint degeneration in the joint occurs and smooth "buffered" cartilage is gradually lost, causing the bones rub against each other and wear, as well as the soft joint tissue.
Allergic reactions are a relatively common cause of throat swelling in general, but sometimes the uvula can be affected alone. “This is known as uvular angioedema,” says Dr. Morrison.