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Keratin, type II cytoskeletal 7 also known as cytokeratin-7 (CK-7) or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded by the KRT7 gene. [5] [6] [7] Keratin 7 is a type II keratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.
The term cytokeratin began to be used in the late 1970s, when the protein subunits of keratin intermediate filaments inside cells were first being identified and characterized. [2] In 2006 a new systematic nomenclature for mammalian keratins was created, and the proteins previously called cytokeratins are simply called keratins (human ...
A Toker cell is an epithelial cell with clear cytoplasm in the nipple of some women. [1] Toker cells are believed to develop from sebaceous glands. [1] They are cytokeratin 7 (CK7) positive, in contrast to squamous epithelium. [1]
The carotid body is situated on the posterior aspect of the bifurcation of the common carotid artery. [3]The carotid body is made up of two types of cells, called glomus cells: glomus type I cells are peripheral chemoreceptors, and glomus type II cells are sustentacular supportive cells.
- The right panel shows high magnification on a positive area, confirming adenocarcinoma, as it shows tumor cells with large nuclei and prominent nucleoli. AE1/AE3 is an antibody cocktail that is used in immunohistochemistry , being generally positive in the cytoplasm of carcinomas (cancers of epithelial origin).
In medical and surgical therapy, revascularization is the restoration of perfusion to a body part or organ that has had ischemia. It is typically accomplished by surgical means. [ 1 ] Vascular bypass and angioplasty are the two primary means of revascularization.
general medicine, surgery: varicose veins: superficial vein is percussed proximally; if impulse is felt over vein distally, valvular incompetence is present Budin's sign: Pierre-Constant Budin: surgery, obstetrics: suppurative mastitis: if breast milk flown into a sterile pad is mixed with pus (brown, yellow or bloody traces), mastitis may be ...
Coronary artery bypass surgery aims to prevent death from coronary artery disease and improve quality of life by relieving angina, the associated feeling of chest pain. [1] The decision to perform surgery is informed by studies of CABG's efficacy in different patient subgroups, based on the lesions' anatomy or how well the heart is functioning.