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Most people recover within a week or so. In about 5% of cases, symptoms worsen and can become life-threatening. This is called severe dengue (formerly called dengue hemorrhagic fever or dengue shock syndrome). [21] [23] Severe dengue can lead to shock, internal bleeding, organ failure and even death. [24]
It is not entirely clear why secondary infection with a different strain of dengue virus places people at risk of dengue hemorrhagic fever and dengue shock syndrome. The most widely accepted hypothesis is that of antibody-dependent enhancement (ADE). The exact mechanism behind ADE is unclear.
A viral hemorrhagic fever is a possible cause of the Plague of Athens during the Peloponnesian War. [13] A viral hemorrhagic fever is an alternate theory of the cause of the Black Death and the Plague of Justinian [14] The initial, and currently only, outbreak of Lujo virus in September–October 2008 left four of five patients dead. [15]
Dengue fever, Japanese encephalitis, other hemorrhagic fevers: Regional arbovirus infections: California serogroup virus, Eastern equine encephalitis virus, Powassan virus, St. Louis encephalitis virus, Western equine encephalitis virus: Varicella voster infection- chickenpox, shingles, and unspecified Chickenpox: Chickenpox (regional)
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
The most widely known ADE example occurs with dengue virus. [34] Dengue is a single-stranded positive-polarity RNA virus of the family Flaviviridae. It causes disease of varying severity in humans, from dengue fever (DF), which is usually self-limited, to dengue hemorrhagic fever and dengue shock syndrome, either of which may be life ...
Dengue fever is caused by infection through viruses of the family Flaviviridae. The illness is most commonly transmitted by Aedes aegypti mosquitoes in tropical and subtropical regions. [54] Dengue virus has four different serotypes, each of which are antigenically related but have limited cross-immunity to reinfection. [55]
Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. [1] Symptoms typically begin three to fourteen days after infection. [2] This may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash.