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Referring to a common salt of fluoride, sodium fluoride (NaF), the lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride/kg body weight). [ 2 ] [ 3 ] [ 4 ] Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.2–0.3 mg/kg or 10 to 15 ...
Children affected by allergies in the developed world: [2] 1 in 13 have eczema; 1 in 8 have allergic rhinitis; 3-6% are affected by food allergy; Children in the United States under 18 years of age: [3] Percent with any allergy: 27.2%; Percent with seasonal allergy: 18.9%; Percent with eczema: 10.8%; Percent with food allergy: 5.8%
Dental fluorosis is caused by a higher than normal amount of fluoride ingestion whilst teeth are forming. Primary dentine fluorosis and enamel fluorosis can only happen during tooth formation, so fluoride exposure occurs in childhood. Enamel fluorosis has a white opaque appearance which is due to the surface of the enamel being hypomineralised ...
Respiratory symptoms, Anaphylaxis, oral allergy syndrome, gastrointestinal symptoms, rhinitis, conjunctivitis Shellfish allergies are highly cross reactive, but its prevalence is much higher than that of fish allergy. Shellfish allergy is the leading cause of food allergy in U.S adults. [31]
Symptoms such as fractured hips in the elderly or brittle and weak bones may be caused by fluorine deficiency in the body. [14] Fluoride stimulates bone formation and increases bone density; [15] however, bone with excess fluoride content has an abnormal structure resulting in increased fragility. Thus, fluoride therapy results in large ...
Food allergies: 7.6% of children and 10.8% of adults. [153] Peanut and/or tree nut (e.g. walnut) allergy affects about three million Americans, or 1.1% of the population. [151] 5–7% of infants and 1–2% of adults. A 117.3% increase in peanut allergies was observed from 2001 to 2005, an estimated 25,700 people in England are affected ...
Symptoms are mainly promoted in the bone structure. Due to a high fluoride concentration in the body, the bone is hardened and thus less elastic, resulting in an increased frequency of fractures. Other symptoms include thickening of the bone structure and accumulation of bone tissue, which both contribute to impaired joint mobility.
Topical fluorides are fluoride-containing drugs indicated in prevention and treatment of dental caries, particularly in children's primary dentitions. [1] The dental-protecting property of topical fluoride can be attributed to multiple mechanisms of action, including the promotion of remineralization of decalcified enamel, the inhibition of the cariogenic microbial metabolism in dental plaque ...