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Benzamide is an organic compound with the chemical formula of C 7 H 7 NO. It is the simplest amide derivative of benzoic acid . In powdered form, it appears as a white solid, while in crystalline form, it appears as colourless crystals. [ 5 ]
Benzonitrile is a useful solvent and a versatile precursor to many derivatives. It reacts with amines to afford N-substituted benzamides after hydrolysis. [3] It is a precursor to diphenylmethanimine via reaction with phenylmagnesium bromide followed by methanolysis.
In chemistry, a mole map is a graphical representation of an algorithm that compares molar mass, number of particles per mole, and factors from balanced equations or other formulae. [1] They are often used in undergraduate-level chemistry courses as a tool to teach the basics of stoichiometry and unit conversion. [2] [3] [4]
Benzaldehyde oxime undergoes Beckmann rearrangement to form benzamide, catalyzed by nickel salts [3] or photocatalyzed by BODIPY. [4] Its dehydration yields benzonitrile.It can be hydrolyzed to regenerate benzaldehyde.
Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes, and serine proteases. [4]It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest.
Molar mass: 139.15 g/mol Appearance White solid Density: 1.26 g/cm 3: Melting point: ... Ammonium benzoate can be dehydrated to form benzamide. References
Benzimidazole is a base: . C 6 H 4 N(NH)CH + H + → [C 6 H 4 (NH) 2 CH] +. It can also be deprotonated with stronger bases: . C 6 H 4 N(NH)CH + LiH → Li [C 6 H 4 N 2 CH] + H 2. The imine can be alkylated and also serves as a ligand in coordination chemistry.
In this prototypical example involving benzophenone, the tetrahedral intermediate expels phenyl anion to give benzamide and benzene as the organic products. Benzophenone is a common photosensitizer in photochemistry. It crosses from the S 1 state into the triplet state with nearly 100% yield.