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Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from wine. IUPAC defines dextrans as "Branched poly-α-d-glucosides of microbial origin having glycosidic bonds predominantly C-1 → C-6". [ 1 ]
Controlled drug release by these dextran microparticles is achieved by degradation, which is the breakdown of chemical bonds in the molecular structure of the polymeric network. [1] Dextran microspheres are formulated in many forms including native dextran, dextran as a cross-linker, dextran conjugates, and chemically modified dextran.
Acetalated dextran is a biodegradable polymer based on dextran that has acetal modified hydroxyl groups. After synthesis, the hydrophilic polysaccharide dextran is rendered insoluble in water, but soluble in organic solvents .
Dextran sulphate sodium (DSS), or dextran sodium sulphate (or any of the former with "sulfate") is a synthetic sulphated polysaccharide with anticoagulant activity used in immunological research to induce colitis. [1] [2] Dextran polymer molecules with a molecular weight of 36–50 kDa are frequently used to this end. [2]
Dextrins are a group of low-molecular-weight carbohydrates produced by the hydrolysis of starch [1] and glycogen. [2] Dextrins are mixtures of polymers of D-glucose units linked by α-(1→4) or α-(1→6) glycosidic bonds.
What's even sneakier is that sugar can be listed under numerous names—like dextran, ... Trans fats are created by chemically altering the structure of unsaturated fats to give processed foods a ...
dextran, α-1,6-glucan with α-1,3-branches; ... Within the cell, certain glucans store energy, fortify cellular structure, behave in recognition, and enhance ...
Cellulose, dextran, agarose, and other insoluble complexes are unaffected because they compose inert matrices, hence why they are so often derivatized with strong and weak cation and anion exchangers in chromatography. DEAE-C beads have diethylaminoethyl chains covalently bound to oxygen atoms on the D-glucose subunits of cellulose.
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