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Betamethasone is also used to stimulate fetal maturation of the lungs and cerebral blood vessels. [3] A cream with 0.05% betamethasone appears effective in treating phimosis in boys, [12] and often averts the need for circumcision. [13] [14] [15] Longer-term research is needed on this treatment method. [12]
Long-term use of topical steroids can lead to secondary infection with fungus or bacteria (see tinea incognito), skin atrophy, telangiectasia (prominent blood vessels), skin bruising and fragility. [11] The use of the finger tip unit may be helpful in guiding how much topical steroid is required to cover different areas of the body.
The methasones (or metasones) are a class of corticosteroids [1] which are generally used in dermatology.They are defined by substitution with a methyl group at the C16α or C16β position of the pregnane steroid nucleus.
There is no clear first-line tocolytic agent. [6] [7] Current evidence suggests that first line treatment with β 2 agonists, calcium channel blockers, or NSAIDs to prolong pregnancy for up to 48 hours is the best course of action to allow time for glucocorticoid administration.
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Rarely, long-term application of high-potency topical glucocorticoids around the eyes may induce glaucoma or cataracts. [ 17 ] [ 18 ] [ 19 ] The incorrect use of topical glucocorticoids can worsen or cover the typical clinical signs of the appearance of fungal skin infections .
Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. It is applied as a topical cream, ointment, lotion or gel ( Diprolene ) to treat itching and other skin conditions such as eczema .
Betamethasone valerate is a synthetic glucocorticoid ester. It is the 17-valerate ester of betamethasone . [ 2 ] [ 3 ] Betamethasone valerate is often used to treat mild eczema with good efficacy and lower incidence of steroid induced adverse effects due to its lower potency compared to other glucocorticoids. [ 4 ]