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A nanogel is a polymer-based, crosslinked hydrogel particle on the sub-micron scale. [1] [2] [3] These complex networks of polymers present a unique opportunity in the field of drug delivery at the intersection of nanoparticles and hydrogel synthesis.
With an estimated 52.5 million adults in the U.S. affected by arthritis alone and up to 24% of adults experiencing muscle pain during their lifetime, effective topical pain relievers can be life ...
The ability of nanoparticles to deliver drugs to specific targets suggests the potential to limit systemic side-effects and immune responses. [ 15 ] The ability of nanoparticles to carry and release drugs is also largely dependent on characteristics which result from the small size and unique surface area to volume ratio of nanoparticles.
The health and safety hazards of nanomaterials include the potential toxicity of various types of nanomaterials, as well as fire and dust explosion hazards. Because nanotechnology is a recent development, the health and safety effects of exposures to nanomaterials, and what levels of exposure may be acceptable, are subjects of ongoing research.
Nanomaterials exhibit different chemical and physical properties or biological effects compared to larger-scale counterparts that can be beneficial for drug delivery systems. Some important advantages of nanoparticles are their high surface-area-to-volume ratio, chemical and geometric tunability, and their ability to interact with biomolecules ...
A review of websites promoting nasal sprays containing colloidal silver suggested that information about silver-containing nasal sprays on the Internet is misleading and inaccurate. [83] Colloidal silver is also sold in some topical cosmetics , as well as some toothpastes, which are regulated by the FDA as cosmetics (other than drug ingredients ...
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It was approved in 2014 in adult patients with chronic, non-cancer pain. [6] Doses of 25 mg were found safe and well tolerated for 52 weeks. [ 7 ] When given concomitantly with opioid analgesics, naloxegol reduced constipation-related side effects, while maintaining comparable levels of analgesia.
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