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Pulmonary capillary hemangiomatosis (PCH) is a disease affecting the blood vessels of the lungs, where abnormal capillary proliferation and venous fibrous intimal thickening result in progressive increase in vascular resistance. [1] It is a rare cause of pulmonary hypertension, and occurs predominantly in young adults.
The pathophysiology of pulmonary heart disease (cor pulmonale) has always indicated that an increase in right ventricular afterload causes RV failure (pulmonary vasoconstriction, anatomic disruption/pulmonary vascular bed and increased blood viscosity are usually involved [1]), however most of the time, the right ventricle adjusts to an overload in chronic pressure.
Chronic thromboembolic pulmonary hypertension (CTEPH) is a long-term disease caused by a blockage in the blood vessels that deliver blood from the heart to the lungs (the pulmonary arterial tree). These blockages cause increased resistance to flow in the pulmonary arterial tree which in turn leads to rise in pressure in these arteries ...
People with coronary artery disease, or narrowing of the blood vessels supplying their heart, may develop symptoms such as: Chest pain that often gets worse with stress or physical activity ...
Symptoms of a PE may include shortness of breath, chest pain particularly upon breathing in, and coughing up blood. [1] Symptoms of a blood clot in the leg may also be present, such as a red, warm, swollen, and painful leg. [1] Signs of a PE include low blood oxygen levels, rapid breathing, rapid heart rate, and sometimes a mild fever. [11]
Venous thrombosis is the blockage of a vein caused by a thrombus (blood clot). A common form of venous thrombosis is deep vein thrombosis (DVT), when a blood clot forms in the deep veins. If a thrombus breaks off and flows to the lungs to lodge there, it becomes a pulmonary embolism (PE), a blood clot in the
Instead, the left heart fails to pump blood efficiently, leading to pooling of blood in the lungs and back pressure within the pulmonary system. This causes pulmonary edema and pleural effusions. [34] In the absence of pulmonary blood vessel narrowing, the increased back pressure is described as 'isolated post-capillary pulmonary hypertension ...
Symptoms may begin quickly or slowly depending on the size of the embolus and how much it blocks the blood flow. [2] Symptoms of embolisation in an organ vary with the organ involved but commonly include: Pain in the involved body part [2] Temporarily [2] decreased organ function; Later symptoms are closely related to infarction of the affected ...