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  2. Immunoglobulin E - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_E

    Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isoform") that has been found only in mammals. IgE is synthesised by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing four Ig-like constant domains (Cε1–Cε4). [1]

  3. Fragment crystallizable region - Wikipedia

    en.wikipedia.org/wiki/Fragment_crystallizable_region

    In IgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody's two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (C H domains 2–4) in each polypeptide chain.

  4. Isotype (immunology) - Wikipedia

    en.wikipedia.org/wiki/Isotype_(immunology)

    The IgG, IgE and IgA antibody isotypes are generated following class-switching during germinal centre reaction and provide different effector functions in response to specific antigens. IgG is the most abundant antibody class in the serum and it is divided into 4 subclasses based on differences in the structure of the constant region genes and ...

  5. I.G.Y. (What a Beautiful World) - Wikipedia

    en.wikipedia.org/wiki/I.G.Y._(What_a_Beautiful...

    "I.G.Y. (What a Beautiful World)" is a song written and performed by American songwriter, singer and musician Donald Fagen. It was the first track on his platinum-certified debut solo album The Nightfly, and was released in September 1982 as its first single.

  6. Radioallergosorbent test - Wikipedia

    en.wikipedia.org/wiki/Radioallergosorbent_test

    The RAST is a radioimmunoassay test to detect specific IgE antibodies to suspected or known allergens for the purpose of guiding a diagnosis about allergy. [10] [11] IgE is the antibody associated with Type I allergic response: for example, if a person exhibits a high level of IgE directed against pollen, the test may indicate the person is allergic to pollen (or pollen-like) proteins.

  7. What is Behind IGE+XAO Group’s (EPA:IGE) Superior ROE?

    www.aol.com/news/behind-ige-xao-group-epa...

    With an ROE of 18.82%, IGE+XAO Group (ENXTPA:IGE) outpaced its own industry which delivered a less exciting 14.43% over the past year. Superficially, this looks great since we know thatRead More...

  8. Anti-immunoglobulin - Wikipedia

    en.wikipedia.org/wiki/Anti-immunoglobulin

    Anti-IgE Type Description Anti-IgE [huMaE11 (Omalizumab)] This is a recombinant monoclonal antibody to IgE. The antibody binds to IgE circulating in the blood. Therefore, IgE cannot bind to mast cells to trigger a histamine response. Anti-IgE [huMaE11 (Omalizumab)] is used in drugs that treat allergies and asthma. [16] Anti-IgE [TES-C21]

  9. Fc receptor - Wikipedia

    en.wikipedia.org/wiki/Fc_receptor

    In immunology, an Fc receptor is a protein found on the surface of certain cells – including, among others, B lymphocytes, follicular dendritic cells, natural killer cells, macrophages, neutrophils, eosinophils, basophils, human platelets, and mast cells – that contribute to the protective functions of the immune system.