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Myoclonus is usually classified physiologically to optimize treatment. Myoclonus is a precursor effect to myoclonus dystonia and most commonly begins in childhood or adolescence. [4] [5] Myoclonus is classified as cortical, subcortical, peripheral or spinal. Cortical myoclonus is the most common of these four and affects the upper limbs and face.
The cerebral cortex, also known as the cerebral mantle, [1] is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals.It is the largest site of neural integration in the central nervous system, [2] and plays a key role in attention, perception, awareness, thought, memory, language, and consciousness.
Cortical reflex myoclonus is thought to be a type of epilepsy that originates in the cerebral cortex – the outer layer, or "gray matter", of the brain, responsible for much of the information processing that takes place in the brain. In this type of myoclonus, jerks usually involve only a few muscles in one part of the body, but jerks ...
Cortical and basomedial nuclei (main olfactory system) Lateral and basolateral nuclei (frontotemporal cortical system) Extended amygdala. Stria terminalis. Bed nucleus of the stria terminalis; Claustrum; Basal ganglia. Striatum. Dorsal striatum (a.k.a. neostriatum) Putamen; Caudate nucleus; Ventral striatum. Nucleus accumbens; Olfactory tubercle
The hippocampus is a structure in the brain that has been associated with various memory functions. It is part of the limbic system, and lies next to the medial temporal lobe. It is made up of two structures, the Ammon's Horn, and the Dentate gyrus, each containing different types of cells. [1]
The subplate is located beneath the cortical plate. It is named for both its location relative to the cortical plate and for the time frame in which it is created. While the cortical plate matures, the cells located in the subplate establish connections with neurons that have not yet moved to their destination layer within the cortical plate.
A cortical column is a group of neurons forming a cylindrical structure through the cerebral cortex of the brain perpendicular to the cortical surface. [1] The structure was first identified by Vernon Benjamin Mountcastle in 1957. He later identified minicolumns as the basic units of the neocortex which were arranged into columns. [2]
Subcortical dementias includes those diseases which predominantly affects the basal ganglia along with features of cognitive decline. Diseases such as progressive supranuclear palsy , Huntington's chorea and Parkinson's disease are different in many features from the other cortical dementias like Alzheimer's disease .