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Functional genomics uses mostly multiplex techniques to measure the abundance of many or all gene products such as mRNAs or proteins within a biological sample. A more focused functional genomics approach might test the function of all variants of one gene and quantify the effects of mutants by using sequencing as a readout of activity.
Convergent Functional Genomics (CFG) Developed by Alexander Niculescu, MD, PhD, and collaborators starting in 1999, [1] it is an approach for identifying and ...
The calculation of prior probabilities depends on available data from the genome being studied, and the type of analysis being performed. For studies where good reference data containing frequencies of known mutations is available (for example, in studying human genome data), these known frequencies of genotypes in the population can be used to estimate priors.
Genetics nursing is a nursing specialty that focuses on providing genetic healthcare to patients. The integration of genetics into nursing began in the 1980s and has been a slow but important process in improving the quality of healthcare for patients receiving genetic and genomic based care from nurses.
Within metagenomics sequencing, functional metagenomic is a powerful approach for characterizing resistomes; a metagenomic library is generated by cloning the total community DNA extracted from a sample into an expression vector, this library is assayed for antimicrobial resistance by plating on selective media that are lethal to the wild-type ...
Cognitive genomics: Study of the changes in cognitive processes associated with genetic profiles. Comparative genomics: Study of the relationship of genome structure and function across different biological species or strains. Functional genomics: Describes gene and protein functions and interactions (often uses transcriptomics).
ConsensusPathDB: a molecular functional interaction database, integrating information from 12 others; Entrez (National Center for Biotechnology Information) Neuroscience Information Framework (University of California, San Diego): integrates hundreds of neuroscience relevant resources; many are listed below
Functional genomics: In functional genomics research, sequence alignment visualization is employed to study gene expression, regulatory elements, and protein-protein interactions. By visualizing sequence alignments in the context of functional annotations and gene networks, researchers can elucidate the biological functions and regulatory ...