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Meclizine, sold under the brand name Bonine, among others, is an antihistamine used to treat motion sickness and dizziness . [3] It is taken by mouth. [3] Effects generally begin in an hour and last for up to a day. [3] Common side effects include sleepiness and dry mouth. [3] Serious side effects may include allergic reactions. [3]
Effective first generation antihistamines include doxylamine, diphenhydramine, promethazine, meclizine, cyclizine, and cinnarizine. [2] In pregnancy meclizine, dimenhydrinate and doxylamine are generally felt to be safe. [2] Side effects include sleepiness. [2] [41] Second generation antihistamines have not been found to be useful. [2]
Mirtazapine (Remeron) is an antidepressant that also has antiemetic effects. [5] [6] It is a potent histamine H1 receptor antagonist, K i =1.6 nM, [7] and also exhibits notable 5-HT 3 antagonism. [6] Meclizine (Bonine, Antivert)
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Again, this isn't a common side effect. But if you’re experiencing negative mood or personality changes (or any other Ozempic side effects ), talk to your doctor ASAP, say both experts.
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