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Urethral cancer is a rare cancer originating from the urethra. The disease has been classified by the TNM staging system and the World Health Organization. [1] [3] [4] Symptoms include blood in the urine, lump at end of penis, or bloody penile discharge. [2] Diagnosis is established by transurethral biopsy. [1]
It accounts for 95% of bladder cancer cases and bladder cancer is in the top 10 most common malignancy disease in the world and is associated with approximately 200,000 deaths per year in the US. [2] [3] It is the second most common type of kidney cancer, but accounts for only five to 10 percent of all primary renal malignant tumors. [4]
Hematuria can be classified according to visibility, anatomical origin, and timing of blood during urination. [1] [6]In terms of visibility, hematuria can be visible to the naked eye (termed "gross hematuria") and may appear red or brown (sometimes referred to as tea-colored), or it can be microscopic (i.e. not visible but detected with a microscope or laboratory test).
The presence of blood in urine is a common presumptive sign of renal cell carcinoma. The haemoglobin of the blood causes the urine to be rusty, brown or red in colour. Alternatively, urinalysis can test for sugar, protein and bacteria which can also serve as indicators for cancer. A complete blood cell count can also provide additional ...
If medicines are no longer controlling the cancer, other treatments may still be helpful, e.g., palliative care that focuses on preventing or relieving problems the cancer may cause: [27] radiotherapy (or chemoradiation) may shrink or slow tumor growth, relieving symptoms. A urinary diversion might be an option to prevent or relieve a blockage ...
Hemorrhagic cystitis, characterized by blood in the urine, can occur secondary to a number of causes including: infections, radiation therapy, underlying cancer, medications and toxins. [59] Medications that commonly cause this problem include the chemotherapeutic agent cyclophosphamide with rates of 2–40%. [59]
While uncommon in solid tumors, chromosomal translocations are a common cause of these diseases. This commonly leads to a different approach in diagnosis and treatment of hematological malignancies. Hematological malignancies are malignant neoplasms ("cancer"), and they are generally treated by specialists in hematology and/or oncology.
Hemorrhagic cystitis or haemorrhagic cystitis is an inflammation of the bladder defined by lower urinary tract symptoms that include dysuria, hematuria, and hemorrhage.The disease can occur as a complication of cyclophosphamide, ifosfamide and radiation therapy.