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  2. Anti-transglutaminase antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-transglutaminase...

    ATA IgA are more frequently found in Celiac Disease (CD); however, ATA IgG are found in CD and at higher levels when affected individual had the IgA-less phenotype. The IgA-less phenotype is more common in CD than the normal population; however, one haplotype, DQ2.5 is found in most CD, has genetic linkage to the IgA-less gene location.

  3. Anti-gliadin antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-gliadin_antibodies

    The IgG antibody is similar to AGA IgA, but is found at higher levels in patients with the IgA-less phenotype. It is also associated with coeliac disease and non-celiac gluten sensitivity. [5] [6] [7] Anti-gliadin antibodies are frequently found with anti-transglutaminase antibodies.

  4. Coeliac disease - Wikipedia

    en.wikipedia.org/wiki/Coeliac_disease

    An equivocal result on tTG testing should be followed by anti-endomysial antibodies. [21] Guidelines recommend that a total serum IgA level is checked in parallel, as people with coeliac with IgA deficiency may be unable to produce the antibodies on which these tests depend ("false negative").

  5. Selective immunoglobulin A deficiency - Wikipedia

    en.wikipedia.org/wiki/Selective_immunoglobulin_A...

    Selective immunoglobulin A (IgA) deficiency (SIgAD [1]) is a kind of immunodeficiency, a type of hypogammaglobulinemia. People with this deficiency lack immunoglobulin A (IgA), a type of antibody that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract.

  6. Wikipedia:Osmosis/Celiac disease - Wikipedia

    en.wikipedia.org/wiki/Wikipedia:Osmosis/Celiac...

    Tests for the antibodies in the blood can be used clinically to help screen for celiac disease, IgA blood tests for both tTG and endomysial tTG can be effective ways to determine whether someone has Celiac disease, especially in more severe cases, although for more common, mild forms of Celiac, these tests are less effective. Tests for IgA or ...

  7. Gluten-related disorders - Wikipedia

    en.wikipedia.org/wiki/Gluten-related_disorders

    Persons suspected of having celiac disease may undergo serological testing for IgA anti-tissue transglutaminase antibodies (abbreviated anti-tTG antibodies or anti-TG2 antibodies) and anti-endomysial antibodies (abbreviated EMA) provided the IgA-level is high, and if IgA is low, testing for certain IgG antibodies; in case of positive ...

  8. Tissue transglutaminase - Wikipedia

    en.wikipedia.org/wiki/Tissue_transglutaminase

    Serology for anti-tTG antibodies has superseded older serological tests (anti-endomysium, anti-gliadin, and anti-reticulin) and has a strong sensitivity (99%) and specificity (>90%) for identifying celiac disease. Modern anti-tTG assays rely on a human recombinant protein as an antigen. [43]

  9. With some early onset and a large percentage of late onset disease, other disorders appear prior to the coeliac diagnosis [1] or allergic-like responses (IgE or IgA, IgG) markedly increased in GSE. Many of these disorders persist on a strict gluten-free diet (GF diet or GFD), and are thus independent of coeliac disease after triggering.

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