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Polymyositis and the associated inflammatory myopathies have an associated increased risk of cancer. [3] The features they found associated with an increased risk of cancer were older age, age greater than 45, male sex, difficulty swallowing, death of skin cells, cutaneous vasculitis, rapid onset of myositis (<4 weeks), elevated creatine kinase, higher erythrocyte sedimentation rate and higher ...
A wide range of symptoms can indicate if a person has polymyalgia rheumatica. The classic symptoms include: [2] [11] Pain and stiffness (moderate to severe) in the neck, shoulders, upper arms, thighs, and hips, which inhibits activity, especially in the morning, but which usually persists to some degree throughout the day.
Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).
Muscle biopsies, however, are the most reliable tests for diagnosing myositis. [4] There are also a variety of blood tests available that help in the diagnosis of myositis. The doctor may look for an elevation of creatine kinase in the blood, which is indicative of muscle inflammation. [4]
However, other inflammatory conditions, such as lupus, can have a positive anti-NT5C1A. [1] As of 2019, it remains to be established whether a positive anti-NT5C1A antibody test can make muscle biopsy unneeded. [1] Inclusion body myositis MRI. Muscle imaging can help establish the pattern of muscle involvement and selection of a biopsy site. [1]
While neck pain is the second most common cause of disability and cost $100 billion, [2] the NIH budgets only $10 million to the study of neck pain. [3] One of the most common neck pains is between the neck and the shoulder. This is technically over the supraspinatus muscle and not in the neck, but it is still called “neck” pain.
Spinal and bulbar muscular atrophy (SBMA), popularly known as Kennedy's disease, is a rare, adult-onset, X-linked recessive lower motor neuron disease caused by trinucleotide CAG repeat expansions in exon 1 of the androgen receptor (AR) gene, which results in both loss of AR function and toxic gain of function.
Acute calcific tendinitis of the longus colli muscle can occur. This presents with acute onset of neck pain, stiffness, dysphagia and odynophagia, and must be distinguished from retropharyngeal abscess and other sinister conditions. Imaging diagnosis is by CT or MRI, demonstrating calcification in the muscle in addition to retropharyngeal oedema.