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  2. Genetic distance - Wikipedia

    en.wikipedia.org/wiki/Genetic_distance

    This distance assumes that genetic differences arise due to mutation and genetic drift, but this distance measure is known to give more reliable population trees than other distances particularly for microsatellite DNA data. This method is not ideal in cases where natural selection plays a significant role in a populations genetics.

  3. Nucleosome repeat length - Wikipedia

    en.wikipedia.org/wiki/Nucleosome_Repeat_Length

    The nucleosome repeat length, (NRL) is the average distance between the centers of neighboring nucleosomes. NRL is an important physical chromatin property that determines its biological function. NRL can be determined genome-wide for the chromatin in a given cell type and state, or locally for a large enough genomic region containing several ...

  4. Gene delivery - Wikipedia

    en.wikipedia.org/wiki/Gene_delivery

    Electroporators can be used to make the cell membrane permeable to DNA. Electroporation is a method of promoting competence. Cells are briefly shocked with an electric field of 10-20 kV/cm, which is thought to create holes in the cell membrane through which the plasmid DNA may enter. After the electric shock, the holes are rapidly closed by the ...

  5. DNA–DNA hybridization - Wikipedia

    en.wikipedia.org/wiki/DNADNA_hybridization

    In genomics, DNADNA hybridization is a molecular biology technique that measures the degree of genetic similarity between DNA sequences. It is used to determine the genetic distance between two organisms and has been used extensively in phylogeny and taxonomy. [1]

  6. Gene mapping - Wikipedia

    en.wikipedia.org/wiki/Gene_mapping

    There are two distinctive mapping approaches used in the field of genome mapping: genetic maps (also known as linkage maps) [7] and physical maps. [3] While both maps are a collection of genetic markers and gene loci, [8] genetic maps' distances are based on the genetic linkage information, while physical maps use actual physical distances usually measured in number of base pairs.

  7. Physical mapping - Wikipedia

    en.wikipedia.org/wiki/Physical_mapping

    Physical map is a technique used in molecular biology to find the order and physical distance between DNA base pairs by DNA markers. [1] It is one of the gene mapping techniques which can determine the sequence of DNA base pairs with high accuracy. Genetic mapping, another approach of gene mapping, can provide markers needed for the physical ...

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  9. Genetic transformation - Wikipedia

    en.wikipedia.org/wiki/Genetic_transformation

    Naturally competent bacteria carry sets of genes that provide the protein machinery to bring DNA across the cell membrane(s). The transport of the exogenous DNA into the cells may require proteins that are involved in the assembly of type IV pili and type II secretion system, as well as DNA translocase complex at the cytoplasmic membrane. [20]