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Doxylamine succinate is the active ingredient in many over-the-counter sleep aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
The cause of morning sickness is unknown but may relate to changing levels of estrogen and the hormone human chorionic gonadotropin. [2] [9] Some have proposed that morning sickness may be useful from an evolutionary point of view -it may protect both the pregnant woman and the developing embryo just when the fetus is most vulnerable. [1]
The company focuses on women who have severe morning sickness, a condition that is seen in 14% of all pregnancies and has left women turning to Google and Reddit chats searching for answers ...
Scientists are moving forward with researching cures for morning sickness, including testing drugs that block GDF15 from binding to its receptor in the brain, and exposing women to the hormone ...
Expecting women know to anticipate morning sickness, a potentially debilitating side effect that plagues 80% of pregnant women. But scientists haven’t been sure as to why the misery occurs ...
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