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“Inflammation is one of the body’s key mechanisms for maintaining homeostasis, acting as a natural response to injury, infection, allergens or irritation,” says Priya Jaisinghani, M.D ...
[3] [4] cSLE, similar to adult-onset SLE (i.e. aSLE), is caused by an individual's production of antibodies that bind to antigens located in the individual's own cells' nuclei and cytoplasm. These antibody-antigen complexes trigger uncontrolled inflammation and injury in various tissues and organs (see below section on "Inflammation").
Inflammation (from Latin: inflammatio) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. [1] The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin calor , dolor , rubor , tumor , and functio laesa ).
Children up to 18 years old develop a more severe form of SLE termed childhood-onset systemic lupus erythematosus. [4] The cause of SLE is not clear. [1] It is thought to involve a combination of genetics and environmental factors. [5] Among identical twins, if one is affected there is a 24% chance the other one will also develop the disease. [1]
Experts explain the difference between acute and chronic inflammation, as well as medications and lifestyle changes that help reduce inflammation. 5 Signs You Have Inflammation in Your Body Skip ...
Signs of inflammation are gut issues, fatigue, recurring rashes, and joint pain. ... This is because inflammation—your body’s natural immune response—can be found wherever there’s cell or ...
[22] [23] Inflammation is one of the main drivers of growth failure and malnutrition in children with chronic illnesses because it decreases caloric intake and increases both energy demands and energy losses. [22] [23] Consequently, children can experience food aversion, intolerance, malabsorption, and loss of lean muscle and fat. [22] [23]
“Chronic inflammation can affect the whole body, and in many cases displays no symptoms,” says Enright. Over time, it can be linked to many adverse health outcomes, including heart disease ...