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The insulin syringe was the first syringe that is considered low dead space. It was initially created with low dead space for accurate measuring and mixing of fast and slow acting insulin, which had the added benefit of wasting as little of the expensive drug as possible.
The unit of insulin was set by the insulin committee at the University of Toronto. [53] The unit evolved eventually to the old USP insulin unit, where one unit (U) of insulin was set equal to the amount of insulin required to reduce the concentration of blood glucose in a fasting rabbit to 45 m g/d L (2.5 m mol/L). Once the chemical structure ...
The dilution of insulin is such that 1 mL of insulin fluid has 100 standard "units" of insulin. [6] A typical insulin vial may contain 10 mL, for 1000 units. Insulin syringes are made specifically for a patient to inject themselves, and have features to assist this purpose when compared to a syringe for use by a healthcare professional:
Insulin lispro, sold under the brand ... the price of for a vial of Humalog increased from US$35 in 2001 to $234 in 2015, [27] or $10.06 and $29.36 per 100 units. [28]
NPH insulin is cloudy and has an onset of 1–3 hours. Its peak is 6–8 hours and its duration is up to 24 hours. [9]It has an intermediate duration of action, meaning longer than that of regular and rapid-acting insulin, and shorter than long acting insulins (ultralente, glargine or detemir).
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