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Heart muscle is subject to two kinds of stress: physiologic stress, i.e. exercise; and pathologic stress, i.e. disease related. Likewise, the heart has two potential responses to either stress: cardiac hypertrophy, which is a normal, physiologic, adaptive growth; or cardiac remodeling, which is an abnormal, pathologic, maladaptive growth. Upon ...
There are two main causes of muscle fatigue: the limitations of a nerve’s ability to generate a sustained signal (neural fatigue); and the reduced ability of the muscle fiber to contract (metabolic fatigue). Muscle fatigue is not the same as muscle weakness, though weakness is an initial symptom.
Rho Cascade - stress fiber formation. The Rho family of GTPases regulate many aspects of actin cytoskeletal dynamics, including stress fiber formation. RhoA (sometimes referred to as just 'Rho') is responsible for the formation of stress fibers, and its activity in stress fiber formation was first discovered by Ridley and Hall in 1992. [4]
[2] [3] The skeletal muscle cells are much longer than in the other types of muscle tissue, and are also known as muscle fibers. [4] The tissue of a skeletal muscle is striated – having a striped appearance due to the arrangement of the sarcomeres. A skeletal muscle contains multiple fascicles – bundles of muscle fibers.
A muscle cell, also known as a myocyte, is a mature contractile cell in the muscle of an animal. [1] In humans and other vertebrates there are three types: skeletal, smooth, and cardiac (cardiomyocytes). [2] A skeletal muscle cell is long and threadlike with many nuclei and is called a muscle fiber. [3]
Activation of trigger points may be caused by a number of factors, including acute or chronic muscle overload, activation by other trigger points (key/satellite, primary/secondary), disease, psychological distress (via systemic inflammation), homeostatic imbalances, direct trauma to the region, collision trauma (such as a car crash which stresses many muscles and causes instant trigger points ...
A myofibril (also known as a muscle fibril or sarcostyle) [1] is a basic rod-like organelle of a muscle cell. [2] Skeletal muscles are composed of long, tubular cells known as muscle fibers, and these cells contain many chains of myofibrils. [3] Each myofibril has a diameter of 1–2 micrometres. [3]
The term 'fibromyalgia' is from Neo-Latin fibro-, meaning 'fibrous tissues'; Greek μυο- myo-, 'muscle'; and Greek άλγος algos, 'pain'; thus, the term literally means "'muscle and fibrous connective tissue pain'. [15] Fibromyalgia is estimated to affect 2 to 4% of the population. [16] Women are affected about twice as often as men.