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Lathyrism is a condition caused by eating certain legumes of the genus Lathyrus.There are three types of lathyrism: neurolathyrism, osteolathyrism, and angiolathyrism, all of which are incurable, differing in their symptoms and in the body tissues affected.
Neurolathyrism, is a neurological disease of humans, caused by eating certain legumes of the genus Lathyrus.This disease is mainly associated with the consumption of Lathyrus sativus (also known as grass pea, chickling pea, kesari dal, or almorta) and to a lesser degree with Lathyrus cicera, Lathyrus ochrus and Lathyrus clymenum [1] containing the toxin ODAP.
In L. sativus ODAP is synthesized in the young seedlings from the precursor (β-isoxazolin-5-on-2-yl)-alanine, also known as BIA. BIA has not been detected in mature plant parts or ripening seeds. The pathway begins with the formation of BIA from O-acetyl-L-serine (OAS) and isoxazolin-5-on.
Alanine is the simplest α-amino acid after glycine. The methyl side-chain of alanine is non-reactive and is therefore hardly ever directly involved in protein function. [12] Alanine is a nonessential amino acid, meaning it can be manufactured by the human body, and does not need to be obtained through the diet. Alanine is found in a wide ...
L-aspartate L-alanine + CO 2. Hence, this enzyme has one substrate, L-aspartate, and two products, L-alanine and CO 2. This reaction is the basis of the industrial synthesis of L-alanine. [1] This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds.
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[citation needed] During cell culture, L-alanyl-L-glutamine is broken down into L-glutamine which is an essential nutrient for the cells. Because the chemical compound L-alanyl-L-glutamine is broken down a little at a time, the cells have time to use the L-glutamine that is formed before it is broken down into ammonia and pyrrolidine carboxylic ...
β-Methylamino-L-alanine, or BMAA, is a non-proteinogenic amino acid produced by cyanobacteria. BMAA is a neurotoxin . Its potential role in various neurodegenerative disorders is the subject of scientific research.
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