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Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents. [8] [5] Common side effects include nausea, trouble sleeping, aggression, diarrhea, feeling tired, and muscle cramps. [8] [11] Serious side effects may include abnormal heart rhythms, urinary incontinence, and ...
Side-effects and ADRs associated with donepezil can be classified in two main categories: common side-effects, most of them observed in clinical trials with AD patients, and unfrequent or extraordinary side-effects, seen in especial conditions or in small clusters of patients with different pathologies under treatment with other concomitant drugs.
These agents are associated with fewer neuromotor side effects and a lower risk of developing tardive dyskinesia. [37] Studies have tested the use of melatonin, high dosage vitamins, and different antioxidants in concurrence with antipsychotic drugs (often used to treat schizophrenia) as a way of preventing and treating tardive dyskinesia.
Paraoxon and rivastigmine are both acetylcholinesterase inhibitors and butyrylcholinesterase inhibitors. [14] [11] [7]In 2015, the United States Food and Drug Administration's Adverse Event Reporting System database compared rivastigmine to the other ChEI drugs donepezil and galantamine found that rivastigmine was associated with a higher frequency of reports of death as an adverse event.
This article needs more reliable medical references for verification or relies too heavily on primary sources, specifically: Unsourced list of side effects, needs references. Please review the contents of the article and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed
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Aricept – used to slow the progression of Alzheimer's disease Ativan ( lorazepam ) – a benzodiazepine , used to treat anxiety Asendin ( amoxapine ) – an dibenzoxazepine antidepressant
But some research has noted rare but serious side effects of once-weekly, 2.4-milligram (mg) semaglutide injections, such as pancreatitis, acute kidney injury, gallbladder issues, and thyroid cancer.
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