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  2. Acromegaly - Wikipedia

    en.wikipedia.org/wiki/Acromegaly

    The long-acting forms of these drugs must be injected every 2 to 4 weeks for effective treatment. Most people with acromegaly respond to this medication. In many people with acromegaly, GH levels fall within one hour and headaches improve within minutes after the injection. Octreotide and lanreotide are effective for long-term treatment.

  3. Gigantism - Wikipedia

    en.wikipedia.org/wiki/Gigantism

    After treatment with pegvisomant, high growth rates, a feature characteristic of gigantism, can be significantly decreased. [22] Pegvisomant has been seen to be a powerful alternative to other treatments such as somatostatin analogues, a common treatment method for acromegaly, if drug treatment is paired with radiation .

  4. Local gigantism - Wikipedia

    en.wikipedia.org/wiki/Local_gigantism

    Local gigantism affecting second toe of a child Local gigantism or localised gigantism is a condition in which a certain part of the body acquires larger than normal size due to excessive growth of the anatomical structures or abnormal accumulation of substances.

  5. Growth hormone therapy - Wikipedia

    en.wikipedia.org/wiki/Growth_hormone_therapy

    By the middle of the twentieth century, endocrinologists understood the clinical features of growth hormone deficiency. GH is a protein hormone, like insulin, which had been purified from pig and cow pancreases for treatment of type 1 diabetes since the 1920s. However, pig and cow GH did not work at all in humans, due to greater species-to ...

  6. Hyperpituitarism - Wikipedia

    en.wikipedia.org/wiki/Hyperpituitarism

    Hyperpituitarism is a condition due to the primary hypersecretion of pituitary hormones; [3] [medical citation needed] it typically results from a pituitary adenoma.In children with hyperpituitarism, disruption of growth regulation is rare, either because of hormone hypersecretion or because of manifestations caused by local compression of the adenoma.

  7. Diabetes - Wikipedia

    en.wikipedia.org/wiki/Diabetes

    This is an accepted version of this page This is the latest accepted revision, reviewed on 4 January 2025. Group of endocrine diseases characterized by high blood sugar levels This article is about the common insulin disorder. For the urine hyper-production disorder, see Diabetes insipidus. For other uses, see Diabetes (disambiguation). Medical condition Diabetes Universal blue circle symbol ...

  8. Somatotropic cell - Wikipedia

    en.wikipedia.org/wiki/Somatotropic_cell

    If there is an excess of growth hormone, it is usually because of over-secretion of somatotrope cells in the anterior pituitary gland. A significant amount of excess somatotrope secretion before puberty or before the end of new bone tissue growth can lead to gigantism, a disease that causes excess growth of body (e.g. being over 7 ft. tall) and unusually long limbs.

  9. Endocrine disease - Wikipedia

    en.wikipedia.org/wiki/Endocrine_disease

    In endocrinology, medical emergencies include diabetic ketoacidosis, hyperosmolar hyperglycemic state, hypoglycemic coma, acute adrenocortical insufficiency, phaeochromocytoma crisis, hypercalcemic crisis, thyroid storm, myxoedema coma and pituitary apoplexy.