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  2. Buspirone - Wikipedia

    en.wikipedia.org/wiki/Buspirone

    Buspirone has also been found to bind with much higher affinity to the dopamine D 3 and D 4 receptors, where it is similarly an antagonist. [45] A major metabolite of buspirone, 1-(2-pyrimidinyl)piperazine (1-PP), occurs at higher circulating levels than buspirone itself and is known to act as a potent α 2-adrenergic receptor antagonist.

  3. List of side effects of buspirone - Wikipedia

    en.wikipedia.org/wiki/List_of_side_effects_of...

    Cerebrovascular accident (stroke); Myocardial infarction (heart attack); Cardiomyopathy; Congestive heart failure; Bradycardia; Dysphoria; Hallucinations; Feelings of ...

  4. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Celexa – an antidepressant of the SSRI class; Centrax – an anti-anxiety agent; Clozaril – atypical antipsychotic used to treat resistant schizophrenia; Concerta (methylphenidate) – an extended release form of methylphenidate

  5. List of antidepressants - Wikipedia

    en.wikipedia.org/wiki/List_of_antidepressants

    Buspirone (Buspar) – 5-HT 1A receptor partial agonist; Lithium (Eskalith, Lithobid) – mood stabilizer (mechanism of action unknown/unclear) Thyroxine (T 4) – thyroid hormone (thyroid hormone receptor agonist) Triiodothyronine (T 3) – thyroid hormone (thyroid hormone receptor agonist)

  6. Azapirone - Wikipedia

    en.wikipedia.org/wiki/Azapirone

    A common metabolite of several azapirones including buspirone, gepirone, ipsapirone, revospirone, and tandospirone is 1-(2-pyrimidinyl)piperazine (1-PP). [ 47 ] [ 48 ] [ 49 ] 1-PP possesses 5-HT 1A partial agonist and α 2 -adrenergic antagonist actions and likely contributes overall mostly to side effects.

  7. Typical antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Typical_antipsychotic

    Another method is "defined daily dose" (DDD), which is the assumed average dose of an antipsychotic that an adult would receive during long-term treatment. [15] DDD is primarily used for comparing the utilization of antipsychotics (e.g. in an insurance claim database), rather than comparing therapeutic effects between antipsychotics. [ 15 ]

  8. Gepirone - Wikipedia

    en.wikipedia.org/wiki/Gepirone

    Gepirone is indicated for the treatment of major depressive disorder (MDD) in adults. [1] Of 15 clinical trials of gepirone for major depressive disorder submitted to the U.S. Food and Drug Administration (FDA), three were excluded for methodological reasons, three were deemed "failed" and "uninformative", seven were deemed negative and did not demonstrate effectiveness, and two were deemed ...

  9. Hypoactive sexual desire disorder - Wikipedia

    en.wikipedia.org/wiki/Hypoactive_sexual_desire...

    The same is true for the anxiolytic, buspirone, which is a 5-HT 1A receptor agonist similarly to flibanserin. [17] Testosterone supplementation is effective in the short term. [18] However, its long-term safety is unclear. [18]

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