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Maropitant (INN; [3] brand name: Cerenia, used as maropitant citrate , is a neurokinin-1 (NK 1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs [4] [5] and in 2012, for cats. [6]
Uterotonic properties, [5] nausea vomiting, and diarrhea, [12] contraindicated for pregnancy and breast feeding [12] Buckthorn bark and berry alder buckthorn Rhamnus frangula "abdominal pain, diarrhea, potentially carcinogenic, with others can potentiate cardiac glycosides and antiarrhythmic agents" [3] Cascara sagrada bark bearberry Rhamnus ...
Mirtazapine also has some veterinary use in cats and dogs. Mirtazapine is sometimes prescribed as an appetite stimulant for cats or dogs experiencing loss of appetite due to medical conditions such as chronic kidney disease. It is especially useful for treating combined poor appetite and nausea in cats and dogs. [137] [138]
Chlorpromazine may be used as an antiemetic in dogs and cats, or, less often, as a sedative before anesthesia. [73] In horses, it often causes ataxia and lethargy and is therefore seldom used. [72] [73] It is commonly used to decrease nausea in animals that are too young for other common antiemetics.
Dopamine receptor flow chart. Dopamine receptors are all G protein–coupled receptors, and are divided into two classes based on which G-protein they are coupled to. [1] The D 1-like class of dopamine receptors is coupled to Gα s/olf and stimulates adenylate cyclase production, whereas the D 2-like class is coupled to Gα i/o and thus inhibits adenylate cyclase production.
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