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These alloantibodies destroy the patient's platelets leading to thrombocytopenia, a rapid decline in platelet count. [1] PTP usually presents 5–12 days after transfusion, and is a potentially fatal condition in rare cases. Approximately 85% of cases occur in women. [2]
The risk of neonatal thrombocytopenia is increased with: [66] Mothers with a history of splenectomy for ITP; Mothers who had a previous infant affected with ITP; Gestational (maternal) platelet count less than 100,000/uL; It is recommended that pregnant women with thrombocytopenia or a previous diagnosis of ITP be tested for serum antiplatelet ...
Thrombocytopenia in hospitalized alcoholics may be caused by spleen enlargement, folate deficiency, and most frequently, the direct toxic effect of alcohol on production, survival time, and function of platelets. [23] Platelet count begins to rise after 2 to 5 days' abstinence from alcohol.
The U.S. Preventive Services Task Force released a draft recommendation advising against using vitamin D to prevent falls and fractures in people over 60. Pharmacist Katy Dubinsky weighs in.
Although Black people are at an increased risk for TTP, its presentation in Black people does not have any distinguishable features compared to those of other races. [60] Pregnant women and women in the post partum period accounted for a notable portion (12–31%) of the cases in some studies; TTP affects about one in 25,000 pregnancies. [61]
The researchers looked at 181 potential risk factors, and then estimated how likely they are to predict dementia and cognitive impairment for people two, four, and 20 years after they turn 60.
The CDC released new COVID-19 vaccination guidelines for people 65 and up and those who are immunocompromised: Get two shots. Experts explain. What Doctors Want Those Over 65 to Know About Getting ...
Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. HIT predisposes to thrombosis (the abnormal formation of blood clots inside a blood vessel ).
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