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These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Augmentation: [a] Especially when used to treat restless legs syndrome, long-term Pramipexole treatment may exhibit drug augmentation, which is "an iatrogenic worsening of RLS symptoms following treatment with dopaminergic agents" [24] and may include an earlier onset of symptoms during the day or a generalized increase in symptoms.
A ring of floaters or hairs just to the temporal side of the central vision; As a posterior vitreous detachment proceeds, adherent vitreous membrane may pull on the retina. While there are no pain fibers in the retina, vitreous traction may stimulate the retina, with resultant flashes that can look like a perfect circle. [citation needed]
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
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Prolonged QT interval (less common than with most other atypical antipsychotic drugs) [6] Speech disorder; Electrolyte abnormalities including hyponatraemia, hypokalaemia, hypocalcaemia, etc. Hypertension; Dysphagia; Oropharyngeal spasm; Laryngospasm; Hepatitis; Jaundice; Hypersalivation; Chest pain; Urinary retention or incontinence; Alopecia ...
The Best ED Medication for Men: Pros & Cons of Top ED Pills. Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world.