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Recurrent airway obstruction, also known as broken wind, heaves, wind-broke horse, or sometimes by the term usually reserved for humans, chronic obstructive pulmonary disease or disorder (COPD) – it is a respiratory disease or chronic condition of horses involving an allergic bronchitis characterised by wheezing, coughing and laboured breathing.
The degree of these effects in horses after intramuscular injection has relatively little support in the current literature. [35] However, there is much anecdotal evidence of their benefits for synovitis and osteoarthritis, and PSGAGs are very commonly used by veterinarians in the United States involved in racehorse and show horse practice. [ 36 ]
flunixin meglumine – nonsteroidal anti-inflammatory drug used as an analgesic and antipyretic in horses; fluralaner - antiparasitic; frunevetmab - nerve growth factor inhibitor monoclonal antibody used for osteoarthritis in cats; furosemide – diuretic used to prevent exercise-induced pulmonary hemorrhage in horses
Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), analgesic, and antipyretic used in horses, cattle and pigs. It is often formulated as the meglumine salt.In the United States, it is regulated by the U.S. Food and Drug Administration (FDA), and may only be lawfully distributed by order of a licensed veterinarian.
The glycosaminoglycan side chains are polyanionic, which causes adjacent side chains to push each other away and create a "bottle brush", where hyaluronic acid is the stem and the side chains are the bristles. When pressure is exerted on the joint, fluids move between the chondrocytes and synovial fluid, exchanging nutrients. [4]
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