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Exocrine pancreatic insufficiency (EPI) is the inability to properly digest food due to a lack or reduction of digestive enzymes made by the pancreas.EPI can occur in humans and is prevalent in many conditions [1] such as cystic fibrosis, [2] Shwachman–Diamond syndrome, [3] different types of pancreatitis, [4] multiple types of diabetes mellitus (Type 1 and Type 2 diabetes), [5] advanced ...
A pancreatic fistula is an abnormal communication between the pancreas and other organs due to leakage of pancreatic secretions from damaged pancreatic ducts.An external pancreatic fistula is one that communicates with the skin, and is also known as a pancreaticocutaneous fistula, whereas an internal pancreatic fistula communicates with other internal organs or spaces.
Pancreatitis is a condition characterized by inflammation of the pancreas. [1] The pancreas is a large organ behind the stomach that produces digestive enzymes and a number of hormones. [1] There are two main types: acute pancreatitis, and chronic pancreatitis. [1] Signs and symptoms of pancreatitis include pain in the upper abdomen, nausea and ...
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Acute pancreatitis (AP) is a sudden inflammation of the pancreas.Causes include a gallstone impacted in the common bile duct or the pancreatic duct, heavy alcohol use, systemic disease, trauma, elevated calcium levels, hypertriglyceridemia (with triglycerides usually being very elevated, over 1000 mg/dL), certain medications, hereditary causes and, in children, mumps.
The average life expectancy in the U.S. is 77.5 years, according to the Centers for Disease Control and Prevention. But Americans outlive their health spans by 12.4 years, the study found.
A study led by Mayo Clinic found a “widening gap between lifespan and healthspan" among 183 countries. The lead researcher and another doctor discuss the drivers of poor health late in life.
The degree of insulin deficiency is variable. Diabetes can develop from infancy through middle adult life, and some family members who carry the gene remain free of diabetes into later adult life. Most of those who develop diabetes show atrophy of the entire pancreas, with mild or subclinical deficiency of exocrine as well as endocrine function.