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A biosafety cabinet (BSC)—also called a biological safety cabinet or microbiological safety cabinet—is an enclosed, ventilated laboratory workspace for safely working with materials contaminated with (or potentially contaminated with) pathogens requiring a defined biosafety level.
A biosafety cabinet is also easily-confused with a laminar flow cabinet, but like the fume hood is primarily designed to protect the worker rather than the biological samples. This is achieved by drawing surrounding air in and exhausting it through a HEPA filter to remove potentially hazardous microorganisms.
The cabinets themselves are required to have seamless edges to allow easy cleaning. Also, the cabinet and all materials within must be free of sharp edges to reduce the risk of damage to the gloves. In a protective-suit lab, all work must be done in a class II biosafety cabinet by personnel wearing a positive pressure suit. To exit a BSL-4 lab ...
While biocontainment, as defined in the Biosafety in Microbiological and Biomedical Laboratories [18] and Primary Containment for Biohazards: Selection, Installation and Use of Biosafety Cabinets [18] manuals available at the Centers for Disease Control and Prevention website much of the design, implementation and monitoring of protocols are ...
One use of the concept of biocontainment is related to laboratory biosafety and pertains to microbiology laboratories in which the physical containment of pathogenic organisms or agents (bacteria, viruses, and toxins) is required, usually by isolation in environmentally and biologically secure cabinets or rooms, to prevent accidental infection ...
BSL-4 cabinets and "Suit Laboratories" have special engineering and design features to prevent hazardous microorganisms from being disseminated into the outside environment. These biosafety suites , where PPPSs are used, are suites of laboratory rooms which are essentially equivalent to large Class III biosafety cabinets in which the interiors ...
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