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  2. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    Eukaryotes initiate DNA replication at multiple points in the chromosome, so replication forks meet and terminate at many points in the chromosome. Because eukaryotes have linear chromosomes, DNA replication is unable to reach the very end of the chromosomes. Due to this problem, DNA is lost in each replication cycle from the end of the chromosome.

  3. Eukaryotic DNA replication - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_DNA_replication

    During DNA replication, the replisome will unwind the parental duplex DNA into a two single-stranded DNA template replication fork in a 5' to 3' direction. The leading strand is the template strand that is being replicated in the same direction as the movement of the replication fork.

  4. Replication timing - Wikipedia

    en.wikipedia.org/wiki/Replication_timing

    We also know that the replication-timing program changes during development, along with changes in the expression of genes. For many decades now, it has been known that replication timing is correlated with the structure of chromosomes. For example, female mammals have two X chromosomes. One of these is genetically active, while the other is ...

  5. Prokaryotic DNA replication - Wikipedia

    en.wikipedia.org/wiki/Prokaryotic_DNA_replication

    Prokaryotic DNA Replication is the process by which a prokaryote duplicates its DNA into another copy that is passed on to daughter cells. [1] Although it is often studied in the model organism E. coli, other bacteria show many similarities. [2] Replication is bi-directional and originates at a single origin of replication (OriC). [3]

  6. Rolling circle replication - Wikipedia

    en.wikipedia.org/wiki/Rolling_circle_replication

    Rolling circle replication (RCR) is a process of unidirectional nucleic acid replication that can rapidly synthesize multiple copies of circular molecules of DNA or RNA, such as plasmids, the genomes of bacteriophages, and the circular RNA genome of viroids. Some eukaryotic viruses also replicate their DNA or RNA via the rolling circle mechanism.

  7. DNA re-replication - Wikipedia

    en.wikipedia.org/wiki/DNA_re-replication

    The DNA re-replication response is different from the response taken when damage is due to oxygen radical generation. Damage from oxygen radical generations leads to a response from the Myc oncogene, which phosphorylates p53 and H2AX. [16] The ATM/ATR DNA damage network will also respond to cases where there is an overexpression of Cdt1.

  8. Template:DNA replication - Wikipedia

    en.wikipedia.org/wiki/Template:DNA_replication

    To change this template's initial visibility, the |state= parameter may be used: {{DNA replication | state = collapsed}} will show the template collapsed, i.e. hidden apart from its title bar. {{DNA replication | state = expanded}} will show the template expanded, i.e. fully visible.

  9. Circular chromosome - Wikipedia

    en.wikipedia.org/wiki/Circular_chromosome

    At the forefront of the replisome is a DNA helicase that unwinds the two strands of DNA, creating a moving replication fork. The two unwound single strands of DNA serve as templates for DNA polymerase, which moves with the helicase (together with other proteins) to synthesise a complementary copy of each strand. In this way, two identical ...