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Vinca alkaloids are now produced synthetically and used as drugs in cancer therapy and as immunosuppressive drugs. These compounds include vinblastine, vincristine, vindesine , and vinorelbine. Additional researched vinca alkaloids include vincaminol , vineridine , and vinburnine .
Vinca difformis in habitat, Cáceres, Spain. Vinca plants are subshrubs or herbaceous, and have slender trailing stems 1–2 m (3 + 1 ⁄ 2 – 6 + 1 ⁄ 2 ft) long but not growing more than 20–70 cm (8– 27 + 1 ⁄ 2 in) above ground; the stems frequently take root where they touch the ground, enabling the plant to spread widely.
Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor (lesser periwinkle), comprising about 25–65% of its indole alkaloids by weight. It can also be synthesized from related alkaloids. [1]
Vinca major, with the common names bigleaf periwinkle, large periwinkle, greater periwinkle and blue periwinkle, is a species of flowering plant in the family Apocynaceae, native to the western Mediterranean. Growing to 25 cm (10 in) tall and spreading indefinitely, it is an evergreen perennial, frequently used in cultivation as groundcover.
Vinca vine is a perennial. Those pretty variegated leaves last all year long, and their flowers reappear every year. It’s a reliable source of green garden color and adds year-round green as a ...
Vinca minor (common names lesser periwinkle [1] or dwarf periwinkle) is a species of flowering plant in the dogbane family, native to central and southern Europe. Other vernacular names used in cultivation include small periwinkle , common periwinkle , and sometimes in the United States, myrtle or creeping myrtle .
Vinblastine is a vinca alkaloid [9] [2] [10] and a chemical analogue of vincristine. [11] [12] It binds tubulin, thereby inhibiting the assembly of microtubules. [13]Vinblastine treatment causes M phase specific cell cycle arrest by disrupting microtubule assembly and proper formation of the mitotic spindle and the kinetochore, each of which are necessary for the separation of chromosomes ...
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