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Perfusion stress test (with 99mTc labelled sestamibi [15]) is appropriate for select patients, especially those with an abnormal resting electrocardiogram. Intracoronary ultrasound or angiogram can provide more information but is invasive and carries the risk of complications associated with cardiac catheterization procedures. [16]
Technetium (99m Tc) sestamibi (commonly sestamibi; USP: technetium Tc 99m sestamibi; trade name Cardiolite) is a pharmaceutical agent used in nuclear medicine imaging.The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six (sesta=6) methoxyisobutylisonitrile (MIBI) ligands.
Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle (). [1]It evaluates many heart conditions, such as coronary artery disease (CAD), [2] hypertrophic cardiomyopathy and heart wall motion abnormalities.
The stress test can result in three outcomes: Pass, Partly Pass and Fail, based on the comparison of the quantified risks to acceptable risk exposure levels and a penalty system. Phase 3: Decision, during which the results of the stress test are analyzed according to the goal and objectives defined in Phase 1. Critical events (events that most ...
Regadenoson, sold under the brand name Lexiscan among others, is an A 2A adenosine receptor agonist that is a coronary vasodilator that is commonly used in pharmacologic stress testing. It produces hyperemia quickly and maintains it for a duration that is useful for radionuclide myocardial perfusion imaging . [ 1 ]
Cardiac magnetic resonance imaging perfusion (cardiac MRI perfusion, CMRI perfusion), also known as stress CMR perfusion, [1] is a clinical magnetic resonance imaging test performed on patients with known or suspected coronary artery disease to determine if there are perfusion defects in the myocardium of the left ventricle that are caused by narrowing of one or more of the coronary arteries.
Rubidium-82 (82 Rb) is a radioactive isotope of rubidium. 82 Rb is widely used in myocardial perfusion imaging.This isotope undergoes rapid uptake by myocardiocytes, which makes it a valuable tool for identifying myocardial ischemia in Positron Emission Tomography (PET) imaging.
Patients with many risk factors e.g. hypertension, high cholesterol, smoking habit, diabetes, obesity, high stress occupation, family history of heart attack; Patients who are unable to exercise; Patients suspected of heart attack; Patients newly diagnosed with heart failure; Patients with abnormal ECG or treadmill