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The efficacy of arsenic trioxide has also been demonstrated in the treatment of multiple myeloma, in combination with ascorbic acid [56] and bortezomib. [ 57 ] Animal studies have shown that the drug also affects ovarian, [ 58 ] liver, stomach, [ 59 ] prostate, and breast cancers, [ 60 ] as well as gliomas [ 61 ] and pancreatic cancer (in ...
Arsenic trioxide is indicated in combination with tretinoin for treatment of adults with newly-diagnosed low-risk acute promyelocytic leukemia whose acute promyelocytic leukemia is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression; and for induction of remission and consolidation in patients with acute promyelocytic leukemia who are refractory to, or ...
Arsenic Trioxide (ATO) directly binds to GLI1 and GLI2 and inhibits the expression of target genes of the Hedgehog signaling pathway, thereby promoting cancer cell apoptosis and reducing cancer cell growth. [15] [50] ATO has been approved by the FDA for the treatment of acute promyelocytic leukemia.
Arsenic trioxide (As 2 O 3) inhibits cell growth and induces apoptosis (programmed cell death) in certain types of cancer cells, [23] which are normally immortal and can multiply without limit. In combination with all-trans retinoic acid , it is FDA-approved as first-line treatment for promyelocytic leukemia .
During the 17th, 18th, and 19th centuries, a number of arsenic compounds were used as medicines, including arsphenamine (by Paul Ehrlich) and arsenic trioxide (by Thomas Fowler), for treating diseases such as cancer or psoriasis. [96] Arsphenamine, as well as neosalvarsan, was indicated for syphilis, but has been superseded by modern antibiotics.
Higher levels of omega-6 fatty acids often found in ultraprocessed foods may interfere with the immune system’s fight against cancer cells, a new study says.
In homeopathy, arsenicum album (Arsenic. alb. ) is a solution prepared by diluting aqueous arsenic trioxide generally until there is little amounts of Arsenic remaining in individual doses. It is used by homeopaths to treat a range of symptoms that include digestive disorders and, as an application of the Law of Similars , has been suggested by ...
The Autoimmune Protocol (AIP) diet is an elimination diet designed to help reduce inflammation, manage symptoms and improve quality of life for people with autoimmune diseases.