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[34] [35] The US research agency DARPA launched at this time the biotechnology research program ADEPT to develop emerging technologies for the US military. [ 36 ] [ 37 ] The agency recognized the potential of nucleic acid technology for defense against pandemics and began to invest in the field. [ 36 ]
[3] [4] During the 1930s, Joachim Hämmerling conducted experiments with Acetabularia in which he began to distinguish the contributions of the nucleus and the cytoplasm substances (later discovered to be DNA and mRNA, respectively) to cell morphogenesis and development. [5] [6]
The idea of mRNA was first conceived by Sydney Brenner and Francis Crick on 15 April 1960 at King's College, Cambridge, while François Jacob was telling them about a recent experiment conducted by Arthur Pardee, himself, and Monod (the so-called PaJaMo experiment, which did not prove mRNA existed but suggested the possibility of its existence).
Karikó was first introduced to ribonucleic acid, or RNA, in 1978 and said she's been "passionate about this fragile molecule ever since." She was exploring DNA's use of messenger RNA to deliver ...
Two pioneering scientists who created the technology behind life-saving Covid-19 vaccines have won the Nobel Prize in medicine or physiology.
On 18 December 2020, the US FDA granted an EUA for mRNA-1273, the Moderna vaccine. [26] [27] [28] Vaccine manufacturers are awaiting full approvals to name their vaccines. [117] [118] Moderna submitted a request for an EUA for mRNA-1273 to the FDA on 30 November 2020. [119] [120] On 18 December 2020, the FDA granted an EUA for the Moderna ...
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1930s–1950s: Joachim Hämmerling conducted experiments with Acetabularia in which he began to distinguish the contributions of the nucleus and the cytoplasm substances (later discovered to be DNA and mRNA, respectively) to cell morphogenesis and development. [18] [19]