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Tolecusatellitidae is a incertae sedis ssDNA/ssDNA(+) family of biological satellites.The family contains two genera and 131 species. [1] This family of viruses depend on the presence of another virus (helper viruses) to replicate their genomes, as such they have minimal genomes with very low genomic redundancy.
The first animal CRESS-DNA virus to be characterized was the porcine circovirus in 1974, and in 1977, the first genome of an ssDNA virus, the Bean golden mosaic virus, was detailed. Beginning in the 1970s, the families of related members in Monodnaviria began to be organized, Parvoviridae becoming the first ssDNA family recognized with ...
Orthopoxvirus particles. A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase.They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and those that have one strand of DNA in their genome, called single-stranded DNA (ssDNA) viruses. dsDNA viruses primarily belong ...
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Replication follows the ssDNA rolling circle model. [3] After infection of a host cell, the small DNA molecules that have become encapsidated with the genomic ssDNA act as primers . They bind to complementary regions and help in initiation of DNA synthesis by host polymerases .
The virions are icosahedral, non enveloped and ~25 nanometers in diameter. They contain two structural proteins.. Genome map of genus Bidensovirus. The genome is bipartite, unique among ssDNA viruses, with two linear segments of ~6 and 6.5 kilobases (kb).
[+]ssDNA genomes to package into viruses are created from this by a rolling circle mechanism. This is the mechanism by which the double stranded supercoiled genome is nicked on the positive strand by a virus-encoded A protein, also attracting a bacterial DNA polymerase (DNAP) to the site of cleavage. DNAP uses the negative strand as a template ...
Viral replication is nuclear. Entry into the host cell is achieved by penetration into the host cell. Replication follows the ssDNA rolling circle model. DNA templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and nuclear pore export.