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Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene on chromosome 17. [5] MPO is most abundantly expressed in neutrophils (a subtype of white blood cells), and produces hypohalous acids to carry out their antimicrobial activity, including hypochlorous acid, the sodium salt of which is the chemical in bleach.
Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow. Myelo refers to the bone marrow, proliferative describes the rapid growth of blood cells and neoplasm describes that growth as abnormal and uncontrolled.
At least one case of FIP1L1-PDGFRA fusion gene-induced eosinophilic leukemia presenting with myeloid sarcoma and eosinophilia has been reported. This form of myeloid sarcoma is distinguished by its highly successful treatment with imatinib (the recommended treatment for FIP1L1-PDGRGA fusion gene-induced eosinophilic leukemia) rather than more aggressive and toxic therapy.
Myelodysplastic syndrome; Other names: Preleukemia, myelodysplasia [1] [2]: Blood smear from a person with myelodysplastic syndrome. A hypogranular neutrophil with a pseudo-Pelger-Huet nucleus is shown.
Myeloid leukemia is a type of leukemia affecting myeloid tissue.. Types include: Acute myeloid leukemia: A cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production.
Monocytic leukemia is a type of myeloid leukemia characterized by a dominance of monocytes in the marrow.When the monocytic cells are predominantly monoblasts, it can be subclassified into acute monoblastic leukemia.
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The first Leo club was founded in 1957 by Jim Graver, the coach of the Abington High School, Pennsylvania baseball team. He was an active member of the Glenside Lions Club