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The Bountiful Company is an American dietary supplements company. It is owned by Kohlberg Kravis Roberts, which sold most of the company's brands to Pfizer in 2021. [2]It was originally known as Nature's Bounty, Inc. but changed its name to NBTY, Inc. in 1995.
Nitroarginine, or N ω-nitro-l-arginine, also known as L-NOARG, is a nitro derivative of the amino acid arginine. [1] It is an inhibitor of nitric oxide synthase and hence a vasoconstrictor . As such, it finds widespread use as a biochemical tool in the study of nitric oxide and its biological effects.
Only the l-arginine (symbol Arg or R) enantiomer is found naturally. [1] Arg residues are common components of proteins. It is encoded by the codons CGU, CGC, CGA, CGG, AGA, and AGG. [2] The guanidine group in arginine is the precursor for the biosynthesis of nitric oxide. [3] Like all amino acids, it is a white, water-soluble solid.
Arginine alpha-ketoglutarate (AAKG) is a salt of the amino acid arginine and alpha-ketoglutaric acid. It is marketed as a bodybuilding supplement. [1] Peer-reviewed studies have found no increase in muscle protein synthesis or improvement in muscle strength from use of AAKG as a dietary supplement. [1] [2] [3]
Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation. Proc. Natl. Acad. Sci. USA 98: 4202–4208. 2001 PM Bauer, GM Buga, JM Fukuto, AE Pegg and LJ Ignarro. Nitric oxide inhibits ornithine decarboxylase via S-nitrosylation of cysteine 360 in the active site of the enzyme. J. Biol. Chem. 276: ...
Agmatine Metabolic Pathways. Agmatine is a cationic amine formed by decarboxylation of L-arginine by the mitochondrial enzyme arginine decarboxylase (ADC). [8] Agmatine degradation occurs mainly by hydrolysis, catalyzed by agmatinase into urea and putrescine, the diamine precursor of polyamine biosynthesis. [9]
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