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Major adverse cardiovascular events. Major adverse cardiovascular events (MACE, or major adverse cardiac events) is a composite endpoint frequently used in cardiovascular research. [1][2] Despite widespread use of the term in clinical trials, the definitions of MACE can differ, which makes comparison of similar studies difficult.
Cardiovascular disease in a person's parents increases their risk by ~3 fold, [25] and genetics is an important risk factor for cardiovascular diseases. Genetic cardiovascular disease can occur either as a consequence of single variant (Mendelian) or polygenic influences. [ 26 ]
Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), [13] myocardial ischemia, [14] or simply heart disease, involves the reduction of blood flow to the cardiac muscle due to build-up of atherosclerotic plaque in the arteries of the heart. [5][6][15] It is the most common of the cardiovascular ...
The Thrombolysis In Myocardial Infarction (TIMI) Study Group, is an academic research organization (ARO) affiliated with Brigham and Women's Hospital and Harvard Medical School with a focus in the field of cardiovascular disease. The group has its headquarters in Boston, Massachusetts. The TIMI Study Group was founded by physician Eugene ...
Women who had high levels of all three measures were 1½ times more likely to experience a stroke and more than three times as likely to have coronary heart disease, the researchers found.. While ...
Arrhythmogenic cardiomyopathy (ACM) is an inherited heart disease. [1] ACM is caused by genetic defects of parts of the cardiac muscle known as desmosomes, areas on the surface of muscle cells which link them together. The desmosomes are composed of several proteins, and many of those proteins can have harmful mutations.
Cerebrovascular disease includes a variety of medical conditions that affect the blood vessels of the brain and the cerebral circulation. Arteries supplying oxygen and nutrients to the brain are often damaged or deformed in these disorders. [2] The most common presentation of cerebrovascular disease is an ischemic stroke or mini-stroke and ...
HeartScore is the interactive version of SCORE - Systematic COronary Risk Evaluation [1] - a cardiovascular disease risk assessment system initiated by the European Society of Cardiology, using data from 12 European cohort studies (N=205,178) covering a wide geographic spread of countries at different levels of cardiovascular risks.