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Wellbutrin SR and XL are available in generic form in the United States and Canada. In 1997, bupropion was approved by the FDA for use as a smoking cessation aid under the name Zyban. [183] [181] In 2006, Wellbutrin XL was similarly approved as a treatment for seasonal affective disorder. [184] [185]
Hydroxybupropion (code name BW 306U), or 6-hydroxybupropion, is the major active metabolite of the antidepressant and smoking cessation drug bupropion. [1] It is formed from bupropion by the liver enzyme CYP2B6 during first-pass metabolism. [1]
The tests showed that some generic versions of Wellbutrin XL 300 mg didn't perform the same as the brand-name pill in laboratory tests. [14] The FDA investigated these complaints and concluded that the generic version is equivalent to Wellbutrin XL in regard to bioavailability of bupropion and its main active metabolite hydroxybupropion.
But those inactive ingredients comprise as much as 99 percent of a pill or capsule, and they’re there to keep your medication stable, help you absorb the good stuff, help prevent tampering, and ...
Wellbutrin vs Adderall: Differences and Similarities Anxiety and depression are two common mental conditions — it’s estimated that about 40 million adults deal with anxiety and an estimated 21 ...
Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word formulation is often used in a way that includes dosage form .
Zyban (bupropion) – same active ingredient as Wellbutrin, but marketed as a smoking cessation aid Zyprexa ( olanzapine ) – atypical antipsychotic used to treat schizophrenia and bipolar disorder
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