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Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [4] [5] [2] Symptoms in mild cases include high blood pressure and a fast heart rate; usually without a fever. [2]
The observation of this efficacy led to the monoamine hypothesis of depression, which postulates that the deficit of certain neurotransmitters is responsible for depression, and even that certain neurotransmitters are linked to specific symptoms. Normal serotonin levels have been linked to mood and behaviour regulation, sleep, and digestion ...
More severe symptoms include fever, seizures, irregular heartbeat, delirium, and coma. [76] [77] [11] If signs or symptoms arise, discontinue treatment with serotonergic agents immediately. [76] It is recommended to washout 4 to 5 half-lives of the serotonergic agent before using an MAO inhibitor. [78]
Being female — binge eating disorder is more common in women than men Having type 1 or type 2 diabetes — perhaps because of the increased focus on food and weight Experiencing childhood trauma ...
The reason why serotonin levels are only high in dominant males, but not dominant females has not yet been established. [ 68 ] In humans, levels of 5-HT 1A receptor inhibition in the brain show negative correlation with aggression, [ 69 ] and a mutation in the gene that codes for the 5-HT 2A receptor may double the risk of suicide for those ...
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Long COVID symptoms, such as brain fog, could be caused by a reduction in serotonin levels, new study finds. Experts explain.
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into the ...