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1,4-Butanediol, also called Butane-1,4-diol (other names include 1,4-B, BD, BDO and 1,4-BD), [5] is a primary alcohol and an organic compound with the formula HOCH 2 CH 2 CH 2 CH 2 OH. . It is a colorless viscous liquid first synthesized in 1890 via acidic hydrolysis of N,N'-dinitro-1,4-butanediamine by Dutch chemist Pieter Johannes Dekkers, who called it "tetramethylene glyco
United States v. Washam (2002) 312 F.3d 926, 930 was an appellate decision for the eighth judicial circuit in which it was considered whether the drug 1,4-Butanediol (1,4-B) was a controlled substance analogue in the United States. The controlled drug which it was alleged 1,4-B was substantially similar to was gamma-hydroxybutyrate (GHB). 1,4-B GHB
15 day advanced DEA notice required for imports, exports, and transshipments X X ... 1,4-Butanediol: GHB and Gamma-Butyrolactone: Cyclohexanone: phencyclidine
2-methylpropane-1,2-diol; 2-methylpropane-1,3-diol; and one unstable geminal diol: 2-methylpropane-1,1-diol (not a glycol), hydrate of 2-methylpropanal (isobutyraldehyde) These three methylpropanediols are structural isomers of butanediols. They are not chiral.
Legislation entering into force on 1 April 2011 made it possible to handle narcotics for industrial purposes and enabled GBL and 1,4-Butanediol to be classified as controlled substances. [39] As of 2023 there are penalties for possessing, selling or driving under the influence of the substance. [40]
Busulfan was approved by the US Food and Drug Administration (FDA) for treatment of chronic myeloid leukemia (CML) in 1999. Busulfan was the mainstay of the chemotherapeutic treatment of chronic myeloid leukemia (CML) until it was displaced by the new gold standard, imatinib, though it is still in use to a degree as a result of the drug's relative low cost.
An assortment of several designer drugs. Designer drugs are structural or functional analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug while avoiding detection or classification as illegal.
Example of a 1,2-diol (Ethyleneglycol, top),a 1,3-diol (1,3-Propanediol, middle)and a 1,4-diol (1,4-Butanediol, bottom).An alkanediol, composed of alkane and diol, are a group of substances consisting of linear or branched hydrocarbon chains containing exactly two hydroxy groups at different positions.