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Vaginal yeast infections are typically caused by the yeast species Candida albicans. Candida albicans is a common fungus often harbored in the mouth, digestive tract, or vagina without causing adverse symptoms. [6] The causes of excessive Candida growth are not well understood, [7] but some predisposing factors have been identified.
Fenticonazole is an imidazole antifungal drug, used locally as the nitrate in the treatment of vulvovaginal candidiasis.It is active against a range of organisms including dermatophyte pathogens, Malassezia furfur, and Candida albicans.
Vulvovaginal candidiasis was first described in 1849 by Wilkinson. [85] In 1875, Haussmann demonstrated the causative organism in both vulvovaginal and oral candidiasis is the same. [85] With the advent of antibiotics following World War II, the rates of candidiasis increased. The rates then decreased in the 1950s following the development of ...
Ibrexafungerp is indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). [1] [4]Ibrexafungerp is currently undergoing late-stage clinical trials for an intravenous formulation for the treatment of various fungal diseases, including life-threatening fungal infections caused primarily by Candida (including C. auris) and Aspergillus species.
The yeast Candida albicans is the most common cause of vaginitis. Specific forms of vaginal inflammation include the following types: Infectious vaginitis accounts for 90% of all cases in reproductive age women: Candidiasis: vaginitis caused by proliferation of Candida albicans, Candida tropicalis, Candida krusei [14]
Vaginal wet mount showing slings of pseudohyphae of Candida albicans surrounded by round vaginal epithelial cells, conferring a diagnosis of candidal vulvovaginitis.. A vaginal wet mount (or vaginal smear [1] or wet prep [2]) is a gynecologic test wherein a sample of vaginal discharge is observed by wet mount microscopy by placing the specimen on a glass slide and mixing with a salt solution. [1]
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