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Severe cutaneous adverse reactions (SCARs) are a group of potentially lethal adverse drug reactions that involve the skin and mucous membranes of various body openings such as the eyes, ears, and inside the nose, mouth, and lips. In more severe cases, SCARs also involves serious damage to internal organs. SCARs includes five syndromes:
Dermatomyositis (DM) is a long-term inflammatory disorder which affects the skin and the muscles. [1] Its symptoms are generally a skin rash and worsening muscle weakness over time. [1] These may occur suddenly or develop over months. [1] Other symptoms may include weight loss, fever, lung inflammation, or light sensitivity. [1]
Familial disseminated comedones without dyskeratosis (FDCWD) is a rare autosomal dominant skin disorder characterized by the presence of numerous comedones (blackheads and whiteheads) on the face, trunk, and extremities. [1] The comedones are typically asymptomatic and do not lead to scarring.
Acrocyanosis may be a sign of a more serious medical problem, such as connective tissue diseases and diseases associated with central cyanosis. Other causative conditions include infections, toxicities, antiphospholipid syndrome, cryoglobulinemia, neoplasms. In these cases, the observed cutaneous changes are known as "secondary acrocyanosis".
The word impetigo is the generic Latin word for 'skin eruption', and it stems from the verb impetere 'to attack' (as in impetus). [29] Before the discovery of antibiotics, the disease was treated with an application of the antiseptic gentian violet , which was an effective treatment.
Other characterizations found on newborns with Leiner's disease are a patch or a large patch of red skin normally on the bottom and spreads to the rest of the body. [2] This disease is also listed as a "rare disease", meaning that a small percent of the population, fewer than 200,000 people in the United States, will have this disorder.
A wound is any disruption of or damage to living tissue, such as skin, mucous membranes, or organs. [1] [2] Wounds can either be the sudden result of direct trauma (mechanical, thermal, chemical), or can develop slowly over time due to underlying disease processes such as diabetes mellitus, venous/arterial insufficiency, or immunologic disease. [3]
Lupus vulgaris, a skin disease with painful cutaneous tuberculosis lesions; Pemphigus vulgaris, the most common form of pemphigus, a rare group of blistering autoimmune diseases that affect the skin and mucous membranes; Psoriasis vulgaris, the plaque psoriasis, the most common form of psoriasis; Sycosis vulgaris, the barber's itch, a once ...