Search results
Results from the WOW.Com Content Network
The term was coined by Joseph Marius DallaValle in his book Micromeritics: The Technology of Fine Particles (1948). [1] It was derived from the Greek words Greek: μικρο, romanized: micro meaning "small" and Greek: μέρος, romanized: méros meaning "part". [6] The size range which he covered in the book was from 10 −1 to 10 5 micrometers.
It is applied in several technological processes in the chemical and pharmaceutical industries. Typically, granulation involves agglomeration of fine particles into larger granules, typically of size range between 0.2 and 4.0 mm depending on their subsequent use. Less commonly, it involves shredding or grinding solid material into finer ...
In manufacturing of compressed tablets, the mixing or blending of several solid pharmaceutical ingredients is easier and more uniform if the ingredients are about the same size. This provides a greater uniformity of dose. A fine particle size is essential in the case of lubricant mixing with granules for its proper function.
Pharmaceutical manufacturing is the process of industrial-scale synthesis of pharmaceutical drugs as part of the pharmaceutical industry. The process of drug manufacturing can be broken down into a series of unit operations , such as milling , granulation , coating , tablet pressing , and others.
The spray drying technique was first described in 1860 with the first spray dryer instrument patented by Samuel Percy in 1872. [citation needed] With time, the spray drying method grew in popularity, at first mainly for milk production in the 1920s and during World War II, when there was a need to reduce the weight and volume of food and other materials.
Particle diameter and particle density significantly affect the drug deposition pattern in the respiratory tract, and are the most common considerations for formulation of pulmonary drugs. Drug particles with diameter larger than 5 μm, predominantly deposit on the upper respiratory tract, limiting the amount of drug particles reaching the lung.
The tiny pollutants emitted by fossil fuel combustion and wildfires may be raising the risk of adverse birth outcomes, a study has found. Exposure to fine particulate matter (PM 2.5) can cause ...
Glatt has shaped and constantly further developed this technology. Initially used solely as a dryer, the fluid bed unit has – by using suitable spraying systems – become a granulator and then – with the relevant developments – a particle coater. Today, fluid bed units are available for batch as well as for continuous production.