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While needlestick injuries have the potential to transmit bacteria, protozoa, viruses and prions, [6] the risk of contracting hepatitis B, hepatitis C, and HIV is the highest. [7] The World Health Organization estimated that in 2000, 66,000 hepatitis B, 16,000 hepatitis C, and 1,000 HIV infections were caused by needlestick injuries.
In the case of HIV exposure, post-exposure prophylaxis (PEP) is a course of antiretroviral drugs which reduces the risk of seroconversion after events with high risk of exposure to HIV (e.g., unprotected anal or vaginal sex, needlestick injuries, or sharing needles). [22]
The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. [1] There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple drugs that act on different viral targets is known as highly active antiretroviral therapy ...
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Transmission-based precautions are infection-control precautions in health care, in addition to the so-called "standard precautions". They are the latest routine infection prevention and control practices applied for patients who are known or suspected to be infected or colonized with infectious agents, including certain epidemiologically important pathogens, which require additional control ...
Needleless connectors (also known as NC's) were developed to reduce needlestick injuries, which occurs when the skin is accidentally punctured by a used needle. [2] Needlestick injuries can be very serious and potentially expose a healthcare professional to bloodborne infectious diseases such as HIV/AIDS, Hepatitis B and Hepatitis C. [3] [4]
The US Institute of Medicine evaluated the conflicting evidence of both Drs Wodak [78] and Käll [79] in their Geneva session [80] and concluded that although multicomponent HIV prevention programmes that include needle and syringe exchange reduced intermediate HIV risk behavior, evidence regarding the effect of needle and syringe exchange ...
The FDA approved the drug (via the then-new FDA accelerated approval system) for use against HIV, AIDS, and AIDS Related Complex (ARC, a now-obsolete medical term for pre-AIDS illness) on March 20, 1987. [69] The time between the first demonstration that AZT was active against HIV in the laboratory and its approval was 25 months.