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Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...
Progesterone (P4), sold under the brand name Prometrium among others, is a medication and naturally occurring steroid hormone. [20] It is a progestogen and is used in combination with estrogens mainly in hormone therapy for menopausal symptoms and low sex hormone levels in women.
Dydrogesterone, sold under the brand name Duphaston among others, [1] is a progestin medication which is used for a variety of indications, including threatened or recurrent miscarriage during pregnancy, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhea, irregular cycles, premenstrual syndrome, and as a component of menopausal ...
Modified-release dosage and its variants are mechanisms used in tablets (pills) and capsules to dissolve a drug over time in order to be released more slowly and steadily into the bloodstream, while having the advantage of being taken at less frequent intervals than immediate-release (IR) formulations of the same drug.
In rats, a dosage of CPA of 25 mg/kg/day results in complete regression of prostate gland growth in gonadally intact males. [48] The equivalent dosage in humans, on the basis of body surface (conversion factor from rat to human of 6), was estimated to be approximately 4 mg/kg/day, or around 300 mg/day CPA for a 75 kg (165 lb) man. [48]
If the pool is used for Olympic Games or World Championships, then the minimum depth is increased to 2 metres (6 ft 7 in). [3] Whereas the Water Cube pool used for the 2008 Olympics was 3 metres (9 ft 10 in) deep, the temporary pool used in 2024 was only 2.2 metres (7 ft 3 in), which commentators suggested made for slower race times. [4]
Deepspot is a 45-metre (148 ft) deep swimming pool and scuba diving training center, located near Warsaw in Mszczonów, Poland.It held the record for being the deepest swimming pool in the world until June 2021, [a] [1] when the 60-metre (200 ft) Deep Dive Dubai was opened.
Erdosteine is a molecule with mucolytic activity. Structurally it is a thioether derivative with two thioether groups. [1] These two functional organosulfur groups contained in the molecule are released following first-pass metabolism with the conversion of erdosteine into its pharmacologically active metabolite Met-I.