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Glycosphingolipids are a subtype of glycolipids containing the amino alcohol sphingosine. They may be considered as sphingolipids with an attached carbohydrate. Glycosphingolipids are a group of lipids (more specifically, sphingolipids) and are a part of the cell membrane. They consist of a hydrophobic ceramide part and a glycosidically bound ...
Glycolipid. Glycolipids are lipids with a carbohydrate attached by a glycosidic (covalent) bond. [ 1 ] Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune response and in the connections that allow cells to connect to one another to form tissues. [ 2 ]
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A sphingolipid with a terminal hydroxyl group is a ceramide. Other common groups bonded to the terminal oxygen atom include phosphocholine, yielding a sphingomyelin, and various sugar monomers or dimers, yielding cerebrosides and globosides, respectively. Cerebrosides and globosides are collectively known as glycosphingolipids.
Voxelotor, sold under the brand name Oxbryta, is a medication used for the treatment of sickle cell disease. [1] [3] [4] [5] [6] Voxelotor is the first hemoglobin ...
The major sphingoid base of mammals is commonly referred to as sphingosine. Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide -linked fatty acid. The fatty acids are typically saturated or mono-unsaturated with chain lengths from 16 to 26 carbon atoms. [ 25 ]: 421–2.
Glycerophospholipids are derived from glycerol-3-phosphate in a de novo pathway. [ 3 ] The term glycerophospholipid signifies any derivative of glycerophosphoric acid that contains at least one O - acyl, or O - alkyl, or O -alk-1'-enyl residue attached to the glycerol moiety. [ 4 ] The phosphate group forms an ester linkage to the glycerol.
In the United States, Vietnamese is the sixth most spoken language, with over 1.5 million speakers, who are concentrated in a handful of states. It is the third-most spoken language in Texas and Washington; fourth-most in Georgia, Louisiana, and Virginia; and fifth-most in Arkansas and California. [ 40 ]